Central hotels in Panama City

Multiple accommodations for your stay
Check-in date:
26 Mar 2026
Check-out date:
27 Mar 2026
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181 results found

Wyndham Garden Panama City

10 58Th Street, Panama City, Panama (Open map)

The hotel is about 5 km from Paitilla airport and 3.3 km from such cultural venues as Museo Panama Viejo. The modern Wyndham Garden...
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Hotel Milan Panama

Avenida Eusebio A Morales, El Cangrejo, Panama City, Panama (Open map)

Balboa Boutiques is located just 1.8 km from the hotel, while Avenida Balboa Waterside Road is 2.3 km away. Featuring 51 rooms,...
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8.6
Fabulous
2432 reviews

Riande Urban Hotel

Calle Eusebio A Morales El Cangrejo, Panama City, Panama (Open map)

The hotel puts you in the centre of Panama City, 10 minutes' drive from Metropolitan National Park. Nestled in the business district...
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8.4
Very Good
1519 reviews

W Panama

Calle 50 And Aquilino De La Guardia, Panama City, Panama (Open map)

This 5-star hotel is conveniently situated a short way from Multicentro. Located in the very heart of Panama City, W Panama Hotel...
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8.5
Fabulous
424 reviews

Holiday Inn Panama Distrito Financiero By Ihg

Calle Ricardo Arango Y Calle 53E Obarrio, Panama City, Panama (Open map)

The exclusive Punta Paitilla is 10 minutes by car from this Panama City hotel, while the non - profit and public Canal Museum of...
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8.3
Very Good
1019 reviews

Tryp By Wyndham Panama Centro

Via Veneto, El Cangrejo, Panama City, Panama (Open map)

Soho stands 3.1 km away, and Metropolitan National Park is only 1.9 km from this Panama City hotel. Featuring a restaurant, the...
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8.6
Fabulous
4266 reviews

Hotel Parador

Calle Eusebio A. Morales, El Cangrejo, Panama City, Panama (Open map)

This comfortable hotel has a comfortable location 4.2 km from the non - profit and public Canal Museum of Panama. Hotel Parador...
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7.9
Good
4212 reviews

Panama House Bed & Breakfast

El Carmen, Calle 1Ra., Casa No 32, Panama City, Panama (Open map)

This smoke-free hotel is centrally situated about 10 minutes by car from Centro de Visitantes del Parque Natural Metropolitano...
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8.4
Very Good
720 reviews

Global Hotel Panama

Calle 54 Este Y Avenida Samuel Lewis, Obarrio, Panama City, Panama (Open map)

This boutique-style hotel offers a location in the very heart of Panama City, 350 metres from Bingo 90. Offering an outdoor swimming...
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8.6
Fabulous
1955 reviews

Novotel Panama City

Calle Jose I. Fabregas y Thais De Pons. alado de la casa de Roberto Durán, Panama City, Panama (Open map)

The comfortable hotel is nestled near a commercial district 500 metres from Habla Ya Spanish for Travelers. The smoke-free Novotel...
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8.5
Fabulous
1432 reviews

Hotel Las Americas Golden Tower Panama

Balboa Avenue and 53 Street Marbella, Panama City, Panama (Open map)

The 5-star hotel is strategically situated 2.9 km from Cinta Costera. Featuring Wi-Fi in public areas, Hotel Las Americas Golden...
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8.5
Fabulous
1626 reviews

Best Western Plus Panama Zen Hotel

Gaspar Hernandez Calle Gaspar O.Hernandez, Panama City, Panama (Open map)

A privileged setting in the centre of Panama City, near an underground station, offers access to the office F&F Tower, which is 17...
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8.6
Fabulous
1859 reviews

Blu Hostel

Calle 53 Oeste (Dr Alberto Navarro), Panama City, Panama (Open map)

The local shopping options feature ATLAPA Conventions Center (3.4 km) and Plaza de Francia (4.5 km). Featuring Wi-Fi throughout the...
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7.7
Good
1169 reviews

Hotel Principe

El Cangrejo, Calle Alberto Navarro Y Jose Fabrega,, Panama City, Panama (Open map)

Notable for its location, 2.3 km from ATLAPA Conventions Center in the Bella Vista district, the hotel is 2.6 km from Avenida Balboa...
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8.7
Fabulous
5649 reviews

Ac Hotel By Marriott Panama City

Calle Ricardo Arias 14, Campo Alegre Area Bancaria, Panama City, Panama (Open map)

Situated in the historic part of Panama City, the hotel is within easy reach of Iglesia del Carmen underground station. The 4-star...
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7.9
Good
320 reviews

Aloft Panama

Via Israel & Calle 76, San Francisco, Panama City, Panama (Open map)

Within 10 minutes' drive of Metropolitan National Park, the modern hotel is also around 25 minutes' walk from Conjunto Monumental de...
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8.3
Very Good
763 reviews

Residence Inn By Marriott Panama City

Calle Ramon H Jurado, Calle Tomas Gabriel Duque, Edificio Pacific Center, Panama City, Panama (Open map)

This Panama City hotel is nestled 4.1 km from the non-profit and public Canal Museum of Panama and 2.4 km from Photo Parador....
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8.9
Fabulous
249 reviews

Crowne Plaza Panama By Ihg

Av. Manuel Espinosa Batista, Panama City, Panama (Open map)

The Cinta Costera is just 1.9 km from this 4-star hotel, while the El Cangrejo neighborhood is 13 minutes' walk away. Featuring a...
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8.3
Very Good
227 reviews

Marinn Place Financial District

Aquilino De La Guardia Y Calle 52, Panama City, Panama (Open map)

The hotel is located 2.1 km from Avenida Balboa Waterside Road and 3.4 km from Monumental Complex of Las Bóvedas. About a 10-minute...
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8.5
Fabulous
7963 reviews

Decapolis Hotel Panama City

Avenida Balboa-Multicentro, Panama City, Panama (Open map)

The comfortable hotel has an unbeatable location in Panama City, approximately 10 minutes' walk from Iglesia del Carmen Station...
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8.1
Very Good
7286 reviews
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