Exceptional design hotels in Panama City

Multiple accommodations for your stay
Check-in date:
17 Feb 2026
Check-out date:
18 Feb 2026
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26 results found

Riu Plaza Panama

Calle 50 Con 53 Este - Urb. Marbella, Panama City, Panama (Open map)

This Panama City hotel is located in the Bella Vista district, 2.3 km from the shopping mall "Multiplaza Pacific". Enticing guests...
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8.6
Fabulous
9238 reviews

Renaissance Panama City Hotel

Via Espana & Ricardo Arias Street, Panama City, Panama (Open map)

Nestled within a casino and a bar, the hotel is nestled near the entertainment district of Panama City. Located within 25 minutes'...
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8.6
Fabulous
196 reviews

Exe Oriental Panama

Obarrio Bella Vista Av. 2 Sur, Panama City, Panama (Open map)

Situated in the financial centre of Panama City within walking distance of a tube station, the welcoming hotel offers access to...
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7.9
Good
1194 reviews

Megapolis Hotel Panama

Avenida Balboa Boulevard Elhayek, Panama City, Panama (Open map)

Balboa Boutiques is a mere 500 metres from the 5-star oceanfront hotel which is also around 550 metres from Majestic Casino....
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8.4
Very Good
3944 reviews

Hotel Casa Panama

Avenida Eloy Alfaro Y Calle 11, Panama City, Panama (Open map)

The hotel is about 5 km from Paitilla airport and about a 10-minute drive from such cultural venues as Punta Culebra Nature Center....
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7.6
Good
1248 reviews

Hotel Tower House Suites

Calle 51, Bella Vista, 36, Panama City, Panama (Open map)

Such city attractions as Casco Viejo, which is 3 km from the hotel, and Cathedral Basilica of St. Located an 18-minute walk from the…
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8.2
Very Good
1379 reviews

Bristol Panama, A Registry Collection Hotel

Calle Aquilino De La Guarida, Panama City, Panama (Open map)

The hotel is situated in the centre of Panama City, only a 5-minute walk from Elite. Offering a swimming pool, the 5-star Bristol…
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9.1
Superb
1000 reviews

Hospedium Princess Hotel Panama

Calle 53 Marbella Y Ave. 5A B Syr, Panama City, Panama (Open map)

The hotel is nestled in the Bella Vista district, 3.4 km from Casco Viejo and 2.6 km from Cinta Costera. The 4-star smoke-free…
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7.0
Good
4293 reviews

Riande Urban Hotel

Calle Eusebio A Morales El Cangrejo, Panama City, Panama (Open map)

The hotel puts you in the centre of Panama City, 10 minutes' drive from Metropolitan National Park. Nestled in the business district...
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8.4
Very Good
1522 reviews

Tryp By Wyndham Panama Centro

Via Veneto, El Cangrejo, Panama City, Panama (Open map)

Soho stands 3.1 km away, and Metropolitan National Park is only 1.9 km from this Panama City hotel. Featuring a restaurant, the...
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8.6
Fabulous
4365 reviews

Hotel Parador

Calle Eusebio A. Morales, El Cangrejo, Panama City, Panama (Open map)

This comfortable hotel has a comfortable location 4.2 km from the non - profit and public Canal Museum of Panama. Hotel Parador...
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7.9
Good
4185 reviews

Global Hotel Panama

Calle 54 Este Y Avenida Samuel Lewis, Obarrio, Panama City, Panama (Open map)

This boutique-style hotel offers a location in the very heart of Panama City, 350 metres from Bingo 90. Offering an outdoor swimming...
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8.6
Fabulous
1926 reviews

Best Western Plus Panama Zen Hotel

Gaspar Hernandez Calle Gaspar O.Hernandez, Panama City, Panama (Open map)

A privileged setting in the centre of Panama City, near an underground station, offers access to the office F&F Tower, which is 17...
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8.6
Fabulous
1879 reviews

Novotel Panama City

Calle Jose I. Fabregas y Thais De Pons. alado de la casa de Roberto Durán, Panama City, Panama (Open map)

The comfortable hotel is nestled near a commercial district 500 metres from Habla Ya Spanish for Travelers. The smoke-free Novotel...
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8.5
Fabulous
1493 reviews

Hotel Principe

El Cangrejo, Calle Alberto Navarro Y Jose Fabrega,, Panama City, Panama (Open map)

Notable for its location, 2.3 km from ATLAPA Conventions Center in the Bella Vista district, the hotel is 2.6 km from Avenida Balboa...
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8.7
Fabulous
5666 reviews

Tantalo Hotel - Kitchen - Roofbar

Avenida B Calle 8 Casco Viejo, Panama City, Panama (Open map)

The 5007-foot-long arch Bridge of the Americas is 2.9 km from this boutique hotel, while Metro bus stop is 450 metres away. Featuring…
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8.4
Very Good
615 reviews

Aloft Panama

Via Israel & Calle 76, San Francisco, Panama City, Panama (Open map)

Within 10 minutes' drive of Metropolitan National Park, the modern hotel is also around 25 minutes' walk from Conjunto Monumental de...
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8.3
Very Good
742 reviews

Marinn Place Financial District

Aquilino De La Guardia Y Calle 52, Panama City, Panama (Open map)

The hotel is located 2.1 km from Avenida Balboa Waterside Road and 3.4 km from Monumental Complex of Las Bóvedas. About a 10-minute...
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8.5
Fabulous
7811 reviews

Decapolis Hotel Panama City

Avenida Balboa-Multicentro, Panama City, Panama (Open map)

The comfortable hotel has an unbeatable location in Panama City, approximately 10 minutes' walk from Iglesia del Carmen Station...
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8.1
Very Good
7314 reviews

Ramada Plaza By Wyndham Panama Punta Pacifica

Via Israel & Calle 71, Panama City, Panama (Open map)

This Panama City hotel is about 5 km from Paitilla airport and 2.4 km from such cultural venues as Museo Panama Viejo. Located only...
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9.1
Superb
2980 reviews
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