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Panama City >
5 stars

5 star hotels in Panama City

Multiple accommodations for your stay
Check-in date:
20 Jun 2026
Check-out date:
21 Jun 2026
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2 guests
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36 results found

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Hyatt Regency Panama City

Calle 52 And Ricardo Arias, Panama City, Panama (Open map)

Situated about a -minute drive from Gulf of Panama, the hotel is also a few moments from the Iglesia del Carmen. Located in a central…
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US$ 104
price for 1 night
RESERVE
9.0
Superb
415 reviews

Aloft By Marriott Panama

Via Israel Calle 76, San Francisco, Panama City, Panama (Open map)

Nearby places of interest include Avenida Balboa, located 3.9 km from the hotel, and the El Cangrejo neighborhood, which is 2.9 km...
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US$ 123
price for 1 night
RESERVE
8.3
Very Good
829 reviews

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Santa Maria Boulevard, Panama City, Panama (Open map)

Panama Viejo Cathedral is within 10 minutes' drive of this Panama City hotel, while the Via España is nestled nearly 15 minutes'...
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US$ 157
price for 1 night
RESERVE
9.4
Superb
458 reviews

Decapolis Hotel Panama City

Avenida Balboa-Multicentro, Panama City, Panama (Open map)

The StarBay Casino is just 0.9 km from the comfortable hotel, which also stands a mere 250 metres from the mainstream Cinemark. The...
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US$ 71
price for 1 night
RESERVE
8.1
Very Good
6925 reviews

Central Hotel Panama Casco Viejo

Casco Antiguo, Avenida Central Calle 5Ta, Panama City, Panama (Open map)

With its exceptional location, the hotel lies approximately 5 minutes' drive from the Paseo de Las Bovedas, while the Mi Pueblito...
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US$ 155
price for 1 night
RESERVE
8.3
Very Good
1691 reviews

Renaissance Panama City Hotel

Via Espana & Ricardo Arias Street, Panama City, Panama (Open map)

The hotel lies km from Gulf of Panama and within 2 km of Photo Parador. The 5-star Renaissance Panama City Hotel, offering a prime…
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US$ 101
price for 1 night
RESERVE
8.6
Fabulous
255 reviews

Saboga Lodge (Adults Only)

Isla Saboga Playa El Coral, Archipielago De Las Perlas, Panama City, Panama (Open map)

You'll need 5-minute drive to Contadora airport. Saboga Lodge Panama City hotel enjoys a beachfront location and provides easy...
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US$ 71
price for 1 night
RESERVE
7.0
Good
133 reviews

Hotel San Felipe

Ave. Central Entre Calle 8A Y 9A, Panama City, Panama (Open map)

Situated about 20 minutes' walk from the French Plaza de Francia, this 5-star hotel also gives access to such sports venues as...
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US$ 86
price for 1 night
RESERVE
8.9
Fabulous
992 reviews

Waymore Hotel Spa & Casino

Avenida Eusebio A. Morales, Panama City, Panama (Open map)

The Camino de Cruces lies 3.5 km away, while University of Panama is not far from this Panama City hotel. The 5-star Waymore Hotel…
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US$ 98
price for 1 night
RESERVE
8.6
Fabulous
3676 reviews

Hostal Yoha

Av. 5A B. Sur, Panama City, Panama (Open map)

This Panama City hotel is 200 m from Balboa Boutiques and within reach of Iglesia del Carmen Station underground station. The 5-star...
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US$ 38
price for 1 night
RESERVE
7.8
Good
682 reviews

Sortis Hotel, Spa & Casino, Autograph Collection

Calle 56 Y 57, Panama City, Panama (Open map)

At the hotel, you'll be 550 m from Estatua Roberto "Mano de Piedra" Duran and 600 m from Nacion Sushi Soho Mall. Offering a central…
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US$ 109
price for 1 night
RESERVE
8.6
Fabulous
320 reviews

Villa Palma Small Luxury Hotel

Calle 1A Oeste, Panama City, Panama (Open map)

You'll need 10-minute drive to Paitilla airport. Located about a 25-minute walk from Ancon Hill, Villa Palma Small Luxury Hotel...
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US$ 220
price for 1 night
RESERVE

La Residence Panama

Calle Beatriz M. De Cabal & Calle 50, Panama City, Panama (Open map)

This Panama City hotel is within a few blocks of the StarBay Casino in the Bella Vista district of Panama City. Located 3.4 km from…
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US$ 158
price for 1 night
RESERVE
9.4
Superb
113 reviews

Hotel Plaza Herrera

San Felipe, Calle 9Na, Casco Viejo,, Panama City, Panama (Open map)

The hotel is about 5 km from Paitilla airport and only 1.8 km from such cultural venues as Museum of Contemporary Art. The 4-star…
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US$ 660
price for 1 night
RESERVE
9.0
Superb
58 reviews

Eurostars Panama City

Calle Ricardo Arias Bellavista Via Espana, Panama City, Panama (Open map)

This Panama City hotel lies km from Gulf of Panama and 2.6 km from the Cinta Costera. The 5-star modern Eurostars Panama City hotel…
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US$ 59
price for 1 night
RESERVE

Dovle Branded Residences By Hms - Preferred Member

Dovle Cincuentenario, Panama City, Panama (Open map)

The hotel is about 5 km from Paitilla airport and approximately 5 minutes by car from such cultural venues as the awkwardly...
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US$ 189
price for 1 night
RESERVE
7.5
Good
35 reviews
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